General Pathology for veterinary students
Opis
Spis treściParamount definitions ... 9 CHAPTER 1.
PATHOLOGY – THE SCIENCE OF DISEASE ... 13Rafał SapierzyńskiIntroduction. General problems: a definition of pathology, division of disciplines in pathology ... 13Pathologist’s workshop ... 16Pathologist’s tasks ... 29References ... 30 CHAPTER 2.
AN OUTLINE OF THE HISTORY OF PATHOMORPHOLOGY ... 31Małgorzata Sobczak-FilipiakJoint history of medicine and veterinary medicine ... 31Pathological anatomy as a separate field of science ... 33Early days of pathomorphology in Poland ... 33Veterinary medicine – vocational education ... 34Pathological anatomy in study curricula ... 35Our collaborators ... 36References ... 39 CHAPTER 3.
ETIOLOGICAL FACTORS ... 41Anna RodoIntroduction ... 41Genetic factors ... 41Physical factors ... 42Biological factors ... 50Chemical factors ... 60Nutritional factors ... 70References ... 73 CHAPTER 4.
EVERYTHING ORIGINATES FROM THE CELL ... 75Katarzyna Kliczkowska KlarowiczIntroduction ... 75Animal cell structure ... 75Osmotic balance in the cell ... 77Mechanisms of cellular damage ... 78References ... 81 CHAPTER 5.
LETHAL DAMAGE, CELL DEATH AND DEATH OF THE ORGANISM ... 83Małgorzata Sobczak-FilipiakIntroduction ... 83Necrosis ... 83Apoptosis ... 94Death of the organism ... 97References ... 106 CHAPTER 6.
SUBLETHAL INJURY – PROGRESSIVE DAMAGE – DEGENERATION ... 107Izabela DolkaIntroduction ... 107Mechanisms of intracellular accumulation ... 109Water and electrolyte metabolism disorders ... 110Protein metabolism disorder including amyloid degeneration ... 113Lipid metabolism disorders ... 137Carbohydrate metabolism disorders ... 147Pigment metabolism disorders ... 150Copper metabolism disorders ... 173Mineral metabolism disorders ... 175References ... 194 CHAPTER 7.
CIRCULATORY SYSTEM DISORDERS ... 197Hanna SendeckaIntroduction ... 197Abnormal filling of blood vessels ... 197Blood cell concentration and structure disorders ... 205Haemorrhages ... 208Coagulation disorders ... 215Embolism and infarction as its consequence ... 223Non-inflammatory oedema ... 228Shock ... 236Blood vessel structure disorders ... 241References ... 244 CHAPTER 8.
TERATOLOGY – CONGENITAL DISORDERS ... 245Rafał SapierzyńskiIntroduction ... 245Pathogenesis of congenital disorders ... 248Causes of congenital disorders ... 249The classification of malformations – structural teratogenesis ... 259References ... 268 CHAPTER 9.
DISORDERS OF CELLULAR GROWTH, MATURATION AND DIFFERENTIATION ... 269Rafał SapierzyńskiIntroduction ... 269Capacity of cells and tissues for proliferation and differentiation ... 272Adaptation ... 275Disorders of growth, maturation and differentiation of cells ... 276References ... 302 CHAPTER 10.
ACUTE INFLAMMATION ... 303Wojciech BieleckiIntroduction ... 303Inflammatory reaction components ... 308The course of acute inflammatory reaction ... 313The morphological picture of acute inflammation ... 316Outcome of acute inflammation ... 325Systemic effects of acute inflammation ... 327References ... 328 CHAPTER 11.
CHRONIC INFLAMMATION AND TISSUE REPAIR ... 329Wojciech BieleckiIntroduction ... 329The role of inflammatory infiltration cells ... 330The mechanism of development and causes of chronic inflammation ... 333Granulomatous inflammation ... 335Tissue repair ... 342References ... 350 CHAPTER 12.
BASICS OF IMMUNOPATHOLOGY ... 351Katarzyna Kliczkowska KlarowiczIntroduction ... 351Immunological response ... 351Immune system cells ... 352Immune system disorders ... 354References ... 372 CHAPTER 13.
NEOPLASIA ... 373Rafał SapierzyńskiIntroduction ... 373General characteristics of neoplasms ... 373Etiopathogenesis of neoplasms ... 399Biological behaviour of malignant neoplasms ... 422Tumour – host relationships ... 443Clinical aspects of neoplastic disease in animals – the outline of clinical oncology ... 459References ... 470